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J Nat Prod. 2002 Jun;65(6):929-31.

New tropane alkaloids from Erythroxylum moonii.

Author information

1
International Center for Chemical Sciences, H.E.J. Research Institute of Chemistry, University of Karachi, Karachi-75270, Pakistan. khattakkf@yahoo.com

Abstract

Four new tropane alkaloids were isolated from the leaves of Erythroxylum moonii and identified as 3 alpha-isobutyryloxy-7 beta-hydroxynortropane (1), 3 alpha-hydroxy-7 beta-phenylacetoxynortropane (2), 3 alpha-cis-cinnamoyloxytropane (3), and 3 alpha-hydroxy-6 beta-(3'-hydroxy-2'-methyl-3'-phenylpropionyloxy)-7 beta-hydroxytropane (4). Other alkaloids isolated for the first time from E. moonii were 3 alpha-benzoyloxytropane, 3 alpha-phenylacetoxytropane, 3 alpha-trans-cinnamoyloxytropane, and 3 alpha-phenylacetoxy-6 beta,7 beta-dihydroxynortropane. The structures of compounds 1-4 were elucidated by spectroscopic methods.

PMID:
12088442
[Indexed for MEDLINE]

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