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Cancer Cell. 2002 Feb;1(1):37-47.

Cancer genomics.

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1
Abramson Family Cancer Research Institute, University of Pennsylvania, Philadelphia 19104, USA. weberb@mail.med.upenn.edu

Abstract

The draft human genome sequence and the dissemination of high throughput technology provides opportunities for systematic analysis of cancer cells. Genome-wide mutation screens, high resolution analysis of chromosomal abberations and expression profiling all give comprehensive views of genetic alterations in cancer cells. From these analyses will come a complete list of the genetic changes that drive malignant transformation and of the therapeutic targets that may be exploited for clinical benefit.

PMID:
12086886
[Indexed for MEDLINE]
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