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Biotechniques. 2002 Jun;Suppl:56-8, 60-1.

BeadArray technology: enabling an accurate, cost-effective approach to high-throughput genotyping.

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1
Illumina, San Diego, CA 92121-1975, USA. aoliphant@illumina.com

Abstract

The Human Genome Project has opened the door to personalized medicine, provided that human genetic diversity can be analyzed in a high-throughput and cost-effective way Illumina has developed a genotyping system that combines very high throughput and accuracy with low cost per SNP analysis. The system uses our BeadArray platform, a high level of multiplexing, and modular, scalable automation to meet the requirements for cost-effective, genome-wide linkage disequilibrium studies. As implemented in a high-throughput genotyping service facility at Illumina, the system has a current capacity of one million SNP assays per day and is easily expandable. Each SNP call is associated with a quality score that correlates with accuracy

PMID:
12083399
[Indexed for MEDLINE]
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