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Dermatol Surg. 2002 Jun;28(6):533-5.

Diagnosis, workup, and prognosis of cutaneous metastases of unknown primary origin.

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1
Department of Dermatology and Dermatologic Surgery, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA.

Abstract

BACKGROUND:

Metastatic cancer of unknown primary (MCUP) accounts for 5-10% of presenting oncology patients. Premorbid identification of the primary source occurs in only 20-25% of cases. A small fraction of these tumors present in the skin and are thus likely to be encountered by dermatologists and dermatologic surgeons.

OBJECTIVE:

To present a practical schema for the diagnosis and evaluation of patients with MCUP.

METHODS:

Case report and literature review.

CONCLUSION:

The diagnosis of MCUP is associated with a poor prognosis, with median survival rates of less than 1 year. Efforts to identify subgroups of patients with understanding of these subgroups will enable early identification of patients with treatable disease and more favorable prognoses.

PMID:
12081687
[Indexed for MEDLINE]
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