Format

Send to

Choose Destination
See comment in PubMed Commons below
Gut. 2002 Jul;51 Suppl 1:i67-71.

Role of visceral sensitivity in the pathophysiology of irritable bowel syndrome.

Author information

1
Gastroenterology Unit, CHU Rangueil, Toulouse, France. 106521.3337@compuserve.com

Abstract

Visceral hypersensitivity has been recognised as a characteristic of patients with irritable bowel syndrome (IBS). It may be involved in the pathogenesis of abdominal pain/discomfort, and seems to result from the sensitisation of nerve afferent pathways originating from the gastrointestinal tract. From a clinical point of view, hypersensitivity, although frequent, is not a constant finding among patients with IBS and cannot therefore be considered as a diagnostic marker of the condition. The advances made in understanding visceral hypersensitivity in patients with IBS are reviewed: the factors that influence abdominal distension are defined and different therapeutic perspectives are examined.

PMID:
12077070
PMCID:
PMC1867713
[Indexed for MEDLINE]
Free PMC Article
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for HighWire Icon for PubMed Central
    Loading ...
    Support Center