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Toxicon. 2002 Jul;40(7):901-8.

Conophysin-R, a Conus radiatus venom peptide belonging to the neurophysin family.

Author information

1
Department of Biology, University of Utah, 257 South 1400 East, Salt Lake City 84112-0840, USA.

Erratum in

  • Toxicon. 2003 Feb;41(2):257.

Abstract

A novel Conus peptide, conophysin-R, was purified from the venom of Conus radiatus. The distinctive disulfide framework and sequence indicates that it is a member of the neurophysin peptide family. The complete sequence of the peptide is HPTKPCMYCSFGQCVGPHICCGPTGCEMGTAEANMCSEEDEDPIPCQVFGSDCALNNPDNIHGHCVADGICCVDDTCTTHLGCLThis is the first time a neurophysin-like peptide has been found in any venom. In addition, conophysin-R is the first neurophysin family member isolated and biochemically characterized from an invertebrate source.

PMID:
12076643
DOI:
10.1016/s0041-0101(02)00079-x
[Indexed for MEDLINE]

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