Clinical-and-hemodynamic manifestations of heart failure were studied in 28 patients with iron deficiency anemia (IDA). Half of the IDA patients have been found out to develop the heart failure syndrome of both systolic and diastolic variant. Decrement in exercise tolerance in the above patients is due to anemia as well as to development and progression of the cardiac muscle dysfunction, which fact warrants an in-depth diagnostic quest together with an optimum treatment.