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Annu Rev Nutr. 2002;22:107-38. Epub 2002 Jan 4.

Nutritional impact of pre- and probiotics as protective gastrointestinal organisms.

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MCP Hahnemann School of Medicine, Pediatric Gastroenterology and Nutrition, Monmouth Medical Center, Long Branch, New Jersey 07740, USA.


The health benefits of pre- and probiotics have been the subject of increased research interests. These food supplements have been demonstrated to alter the pre-existing intestinal flora so as to provide an advantage to the host. This review focuses on the scientific evidence both for and against their role in promoting health and treating disease. Specific attention is turned to their effects on immunomodulation, lipid metabolism, cancer prevention, diarrhea, Helicobacter pylori, necrotizing enterocolitis, allergy, and inflammatory bowel disease.

[Indexed for MEDLINE]

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