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Curr Opin Investig Drugs. 2002 Mar;3(3):437-40.

Cannabis: old medicine with new promise for neurological disorders.

Author information

1
Department of Rehabilitation Medicine, University of Washington School of Medicine, Seattle 98531, USA. gtcarter@u.washington.edu

Abstract

Marijuana is a complex substance containing over 60 different forms of cannabinoids, the active ingredients. Cannabinoids are now known to have the capacity for neuromodulation, via direct, receptor-based mechanisms at numerous levels within the nervous system. These have therapeutic properties that may be applicable to the treatment of neurological disorders; including anti-oxidative, neuroprotective, analgesic and anti-inflammatory actions; immunomodulation, modulation of glial cells and tumor growth regulation. This article reviews the emerging research on the physiological mechanisms of endogenous and exogenous cannabinoids in the context of neurological disease.

PMID:
12054093
[Indexed for MEDLINE]

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