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J Parasitol. 2002 Feb;88(1):199-203.

Cloning and molecular characterization of the cDNA encoding histone H1 from Leishmania braziliensis.

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Departamento de Parasitología, Ecología y Genética, Facultad de Farmacia, Universidad de La Laguna, Tenerife, Spain.


The isolation and molecular characterization of the histone H1-encoding gene from Leishmania braziliensis was carried out. The gene is present in the genome as a single copy and transcribed as a polyadenylated transcript of 830 nucleotides. The deduced amino acid sequence has in its central region the DNA binding K-[K/R]-A-A-[A/P] motif, which is repeated in tandem 9 times.

[Indexed for MEDLINE]

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