Abstract
In a prospective randomised trial, three groups of 20 patients each were compared. A first group served as a control, a second group received dipyridamole and acetylsalicylic acid and a third group received low doses of heparin. The incidence of deep vein thrombosis determined by the 125I-fibrinogen test was 40% in the first group, 50% in the second group, and 5% in the third group. The differences between the heparin group and the two other groups are statistically significant. No wound complication and no haematoma at the injection site occurred.
Publication types
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Clinical Trial
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Comparative Study
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Randomized Controlled Trial
MeSH terms
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Aged
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Aspirin / pharmacology*
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Aspirin / therapeutic use
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Blood Platelets / metabolism
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Dipyridamole / pharmacology*
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Dipyridamole / therapeutic use
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Female
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Heparin / administration & dosage
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Heparin / pharmacology*
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Heparin / therapeutic use
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Humans
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Injections, Subcutaneous
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Male
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Middle Aged
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Platelet Aggregation / drug effects
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Postoperative Complications / prevention & control*
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Prospective Studies
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Thromboembolism / prevention & control*
Substances
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Dipyridamole
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Heparin
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Aspirin