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Annu Rev Neurosci. 2002;25:491-505. Epub 2002 Mar 27.

Multiple sclerosis: deeper understanding of its pathogenesis reveals new targets for therapy.

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1
Department of Neurology and Neurological Sciences, Stanford University School of Medicine, California 94305, USA. steinman@stanford.edu

Abstract

Recent technological breakthroughs allowing for large-scale analysis of gene transcripts and large-scale monitoring of the immune response with protein chips are revealing new participants in the pathogenesis of multiple sclerosis. Some of these participants may be useful targets for therapy.

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