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Cryo Letters. 2002 Mar-Apr;23(2):69-78.

Cryosurgery - a review of recent advances and current issues.

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1
Roswell Park Memorial Institute, State University of New York at Buffalo, 666 Elm Street, 14263,USA. aagee70@aol.com

Abstract

Advances in cryosurgery since 1990 were initiated by the development of improved cryosurgical equipment and by the availability of intraoperative ultrasound to monitor the tissue-freezing process. Interest in research on the effects of freezing on tissue and on new clinical applications was then stimulated. The research led to a better understanding of the mechanisms of cryogenic injury, including cell death by apoptosis, which has emerged as a potential key to the use of adjunctive chemotherapy in the treatment of cancer. Optimization of cryosurgical technique will also improve clinical results.

PMID:
12050774
[Indexed for MEDLINE]
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