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Stat Methods Med Res. 2002 Apr;11(2):91-115.

Multi-state models for event history analysis.

Author information

1
Department of Biostatistics, University of Copenhagen, Danish Epidemiology Science Centre, Copenhagen, Denmark. pka@biostat.ku.dk

Abstract

An introduction to event history analysis via multi-state models in given. Examples include the two-state model for survival analysis, the competing risks and illness-death models, and models for bone marrow transplantation. Statistical model specification via transition intensities and likelihood inference is introduced. Consequences of observational patterns are discussed, and a real example concerning mortality and bleeding episodes in a liver cirrhosis trial is discussed.

PMID:
12040698
DOI:
10.1191/0962280202SM276ra
[Indexed for MEDLINE]

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