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J Cataract Refract Surg. 2002 Jun;28(6):977-81.

Prophylactic intracameral cefuroxime. Efficacy in preventing endophthalmitis after cataract surgery.

Author information

1
Department of Ophthalmology, St. Eriks Hospital, Stockholm, Sweden.

Abstract

PURPOSE:

To evaluate the efficacy of prophylactic intracameral cefuroxime in preventing endophthalmitis in cataract surgery.

SETTING:

Department of Ophthalmology, St. Eriks Hospital, Stockholm, Sweden.

METHODS:

In a noncontrolled retrospective observational study, all cases of recorded postoperative endophthalmitis were related to the total number of uncombined cataract procedures from January 1996 to December 2000.

RESULTS:

Twenty cases of postoperative endophthalmitis occurred in 32180 procedures, yielding an overall rate of 0.06%. Cefuroxime-resistant organisms accounted for 12 of 13 culture-positive cases, and enterococci were the most common etiology.

CONCLUSIONS:

Intracameral cefuroxime 1 mg appeared to effectively inhibit sensitive bacterial strains and was associated with a low frequency of postoperative endophthalmitis. The causative organisms of future incidents of postoperative endophthalmitis will determine whether the present protocol must be reappraised.

PMID:
12036639
[Indexed for MEDLINE]

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