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Biochem J. 2002 Jul 15;365(Pt 2):343-7.

Fate of haem iron in the malaria parasite Plasmodium falciparum.

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1
Department of Chemistry, University of Cape Town, Private Bag, Rondebosch 7701, South Africa. tegan@science.uct.ac.za

Abstract

Chemical analysis has shown that Plasmodium falciparum trophozoites contain 61+/-2% of the iron within parasitized erythrocytes, of which 92+/-6% is located within the food vacuole. Of this, 88+/-9% is in the form of haemozoin. (57)Fe-Mössbauer spectroscopy shows that haemozoin is the only detectable iron species in trophozoites. Electron spectroscopic imaging confirms this conclusion.

PMID:
12033986
PMCID:
PMC1222701
DOI:
10.1042/BJ20020793
[Indexed for MEDLINE]
Free PMC Article
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