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Bioorg Med Chem Lett. 2002 Jun 3;12(11):1521-3.

Synthesis of more potent analogues of the acetylcholinesterase inhibitor, huperzine B.

Author information

1
Drug Discovery Program, Department of Neurology, Georgetown University Medical Center, 3900 Reservoir Road NW, Washington DC 20007-2197, USA.

Abstract

The synthesis and acetylcholinesterase inhibition activity of analogues of huperzine B are reported. These new racemic analogues show a better AChE inhibitory activity than the natural product huperzine B.

PMID:
12031333
[Indexed for MEDLINE]

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