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Curr Biol. 2002 Apr 30;12(9):R322-4.

Asthma: T-bet--a master controller?

Author information

1
Department of Allergy, National Heart and Lung Institute, Biomedical Sciences Division, Faculty of Medicine, Imperial College, London SW7 2AZ, UK. d.s.robinson@ic.ac.uk

Abstract

The transcription factors T-bet and GATA3 are important reciprocal determinants of Th1 and Th2 T helper cell differentiation. Recent evidence suggests that these factors may affect airway immunopathology in asthma.

PMID:
12007433
PMCID:
PMC3807785
[Indexed for MEDLINE]
Free PMC Article
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