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J Antimicrob Chemother. 2002 May;49(5):827-30.

The successful introduction of a programme to reduce the use of i.v. ciprofloxacin in hospital.

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Department of Microbiology, City Hospital NHS Trust, Dudley Road, Birmingham B18 7QH, UK.


The effectiveness of a programme to reduce the use of i.v. ciprofloxacin was assessed. i.v. ciprofloxacin was removed from ward stock and discussion occurred regarding appropriate use of the drug. Six months later, a factsheet containing recommendations was distributed to all medical staff and a requirement for justification before prescription was introduced. The programme reduced expenditure on i.v. ciprofloxacin to 34% of original levels. Savings of > 36,000 pounds sterling were made for two consecutive years. A sustained reduction in the use of i.v. ciprofloxacin was obtained by a combination of education and restriction.

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