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Br J Dermatol. 2002 May;146(5):877-81.

Systemic lupus erythematosus induced by Epstein-Barr virus infection.

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Department of Dermatology, 2nd Floor Outpatients Building, The Royal London Hospital, Whitechapel, London E1 1BB, UK.


We report a 22-year-old woman who developed systemic lupus erythematosus (SLE) immediately after an Epstein-Barr virus (EBV)-induced mononucleosis infection. The link between these two conditions has long been suspected. The close temporal relationship, the course of the pathological events and the development of immunological changes in this case provide further evidence supporting the hypothesis that EBV infection could work as a trigger in some cases of SLE, particularly if the patient is genetically susceptible.

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