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Exerc Sport Sci Rev. 2002 Apr;30(2):75-9.

Exercise enhances and protects brain function.

Author information

1
Institute for Brain Aging and Dementia, University of California, Irvine 92697-4540, USA. cwcotman@uci.edu

Abstract

Physical activity, in the form of voluntary wheel running, induces gene expression changes in the brain. Animals that exercise show an increase in brain-derived neurotrophic factor, a molecule that increases neuronal survival, enhances learning, and protects against cognitive decline. Microarray analysis of gene expression provides further support that exercise enhances and supports brain function.

PMID:
11991541
[Indexed for MEDLINE]

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