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Am J Psychiatry. 2002 May;159(5):863-5.

Prospective diagnosis of the initial prodrome for schizophrenia based on the Structured Interview for Prodromal Syndromes: preliminary evidence of interrater reliability and predictive validity.

Author information

1
Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06520, USA. tandy.miller@yale.edu

Abstract

OBJECTIVE:

This study was conducted to determine the interrater reliability and predictive validity of a set of diagnostic criteria for the prodrome of the first episode of schizophrenic psychosis when based on the Structured Interview for Prodromal Syndromes.

METHOD:

The subjects were patients referred for evaluation because of a suspected schizophrenia prodromal syndrome. For the reliability study, two to four raters independently diagnosed 18 patients on the basis of face-to-face or videotaped interviews. For the validity study, 6- and 12-month outcome data were collected for 29 patients.

RESULTS:

Agreement in differentiating prodromal from nonprodromal patients was 93%. The prodromal features had converted to schizophrenic psychosis for 46% of the prodromal patients at 6 months and for 54% at 12 months.

CONCLUSIONS:

In small groups of subjects, these diagnostic criteria for the schizophrenic prodrome and the Structured Interview for Prodromal Syndromes showed promising interrater reliability and predictive validity.

PMID:
11986145
DOI:
10.1176/appi.ajp.159.5.863
[Indexed for MEDLINE]

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