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Folia Microbiol (Praha). 2002;47(1):3-27.

Psychoactive tryptamines from basidiomycetes.

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Institute of Microbiology, Academy of Sciences of the Czech Republic, 142 20 Prague, Czechia.


The review lists natural sources, i.e. strains and species of fungi producing predominantly psychoactive tryptamines (indolealkylamines), their chemical structure and properties, toxic effects on the man and psychic symptoms of intoxication. It describes the biosynthesis and production of some tryptamines by the mycelial culture of Psilocybe bohemica Sebek, a survey of methods for their analysis and isolation. It evaluates the worldwide use and abuse of psychoactive fungi as sources of drugs in general and in the Czechia in particular during the last two and a half decades.

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