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Neurology. 2002 Apr 23;58(8):1294-6.

Quantitative functional measures in MS: what is a reliable change?

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1
Department of Neurology, University of Rochester Medical Center, NY, USA. Steven_Schwid@urmc.rochester.edu

Abstract

As a first step toward understanding which changes should be considered as meaningful, the authors assessed the reliability of quantitative functional tests on 5 consecutive days in 63 patients with MS, determining the range of measurement variability present when patients are clinically stable. Time to walk 25 feet (T25FW) and the 9-hole peg test (9HPT) varied by <20% of individual mean scores on repeated testing. Therefore, a 20% change on these tests can be considered to be the threshold that reliably indicates a true change in function for an individual.

PMID:
11971105
[Indexed for MEDLINE]
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