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Neurology. 2002 Apr 23;58(8):1288-90.

Improved executive functioning following repetitive transcranial magnetic stimulation.

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Department of Psychiatry, University of Iowa College of Medicine, Iowa City, IA 52240, USA.


The cognitive effects of active and sham repetitive transcranial magnetic stimulation (rTMS) were examined in 19 middle-aged and elderly patients with refractory depression. Patients received either active (n = 9) or sham (n = 10) rTMS targeted at the anterior portion of the left middle frontal gyrus. Patients in the active rTMS group improved significantly on a test of cognitive flexibility and conceptual tracking (Trail Making Test-B).

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