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Neuron. 2002 Apr 11;34(2):175-7.

Have we been hebbing down the wrong path?

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Department of Biomedical Engineering, University of Southern California, Los Angeles, CA 90089, USA.


In this issue of Neuron, Stepanyants, Hof, and Chklovskii derive a simple mathematical formula to calculate, from measurable anatomical parameters, the capacity for neuronal wiring plasticity involving local synaptic rearrangements. Their work provides a deeper understanding of the potential contribution of structural plasticity to learning and memory.

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