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T-cell responses in allergy and asthma.

Author information

1
Section of Clinical Immunology, Allergy, and Respiratory Diseases, Department of Internal Medicine, University of Florence, Florence, Italy. s.romagnani@mednuc2.dfc.unifi.it

Abstract

T-helper-2-type cytokines and some chemokines play an essential role in the pathogenesis of both allergy and asthma. A change in the T-helper 1/T-helper 2 balance, caused by the dramatic change in the microbial environment of children, may account for the increasing prevalence of these conditions, but can also provide a conceptual basis for the development of new therapeutic strategies.

[Indexed for MEDLINE]

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