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Proc Natl Acad Sci U S A. 2002 Apr 16;99(8):4937-40.

Biomimetic self-assembly of a functional asymmetrical electronic device.

Author information

1
Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA 02138, USA.

Abstract

This paper introduces a biomimetic strategy for the fabrication of asymmetrical, three-dimensional electronic devices modeled on the folding of a chain of polypeptide structural motifs into a globular protein. Millimeter-size polyhedra-patterned with logic devices, wires, and solder dots-were connected in a linear string by using flexible wire. On self-assembly, the string folded spontaneously into two domains: one functioned as a ring oscillator, and the other one as a shift register. This example demonstrates that biomimetic principles of design and self-organization can be applied to generate multifunctional electronic systems of complex, three-dimensional architecture.

PMID:
11959945
PMCID:
PMC122698
DOI:
10.1073/pnas.032667599
[Indexed for MEDLINE]
Free PMC Article

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