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Microbes Infect. 2002 Apr;4(5):531-7.

Homeostatic expansion versus antigen-driven proliferation: common ends by different means?

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1
Department of Laboratory Medicine and Pathology, Center for Immunology, University of Minnesota, MMC 334, 420 Delaware St SE, Minneapolis, MN 55455, USA.

Abstract

The requirements for T-cell proliferation driven by "space-filling" (homeostatic expansion) differ significantly from those for antigen-driven responses. Here we review these differences and discuss their implications for regulation of T-cell responses and the size of the T-cell compartment.

PMID:
11959508
[Indexed for MEDLINE]
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