Format

Send to

Choose Destination
See comment in PubMed Commons below
Curr Opin Struct Biol. 2002 Apr;12(2):263-9.

Deriving folds of macromolecular complexes through electron cryomicroscopy and bioinformatics approaches.

Author information

1
Program in Structural and Computational Biology and Molecular Biophysics, Baylor College of Medicine, Houston, Texas 77030, USA. wah@bcm.tmc.edu

Abstract

Intermediate-resolution (7-9A) structures of large macromolecular complexes can be obtained by electron cryomicroscopy. This structural information, combined with bioinformatics data for the individual protein components or domains, can lead to a fold model for the entire complex. Such approaches have been demonstrated with the 6.8 A structure of the rice dwarf virus to derive models for the major capsid shell proteins.

PMID:
11959506
[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Support Center