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J Neural Transm (Vienna). 2002 Mar;109(3):421-31.

Developmental malformations in cerebral structures in "endogenous psychoses".

Author information

1
Department of Psychiatry and Psychotherapy, University of W├╝rzburg, Federal Republic of Germany. beckmann@mail.uni-wuerzburg.de

Abstract

The last decades have revealed several structural deviances in patients with so called "endogenous psychoses". Reasonably well established are the enlargement of the lateral ventricles and subtle structural deficits in temporobasal and orbital frontal structures (hypofrontality) in a majority of schizophrenic patients. It is the aim of this investigation to examine the cytoarchitecture of these important central structures, namely the entorhinal region and the orbitofrontal cortex (Brodmann area 11) which have been under meticulous investigation in our laboratories over decades (for review: Beckmann, 2000).

PMID:
11956962
DOI:
10.1007/s007020200034
[Indexed for MEDLINE]

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