Send to

Choose Destination
See comment in PubMed Commons below
Cell. 2002 Apr 5;109(1):1-4.

Does artemis end the hunt for the hairpin-opening activity in V(D)J recombination?

Author information

  • 1Division of Immunology, Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720, USA.


When complexed with the catalytic subunit of DNA-dependent protein kinase (DNA-PK(cs)), the recently discovered dsDNA break repair protein named Artemis acquires the ability to open hairpin DNA molecules in vitro. Both genetic and biochemical data point toward a physiological role for this complex as the elusive hairpin-opening activity in V(D)J recombination.

[PubMed - indexed for MEDLINE]
Free full text

LinkOut - more resources

Full Text Sources

Other Literature Sources

PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Support Center