Format

Send to

Choose Destination
Neonatal Netw. 2000 Dec;19(8):33-6.

Theophylline or caffeine: which is best for apnea of prematurity?

Author information

1
Women and Infants' Hospital, 101 Dudley Street, Providence, RI 02905-2401, USA. jmbagannon@aol.com

Abstract

Apnea of prematurity is a common problem of the premature infant under 30 weeks gestation. Theophylline and caffeine, two methylxanthines, are widely used to treat this condition. The drugs are equally effective in preventing apnea in the premature infant. Caffeine citrate has many advantages over theophylline, however, including once-a-day dosing, more predictable plasma concentrations, earlier onset of action, and minimal side effects. Caffeine is therefore the initial drug of choice for apnea of prematurity.

PMID:
11949272
DOI:
10.1891/0730-0832.19.8.33
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for HighWire
Loading ...
Support Center