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Trends Biochem Sci. 2002 Apr;27(4):203-8.

Protein-water interactions in a dynamic world.

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Dept Molecular and Structural Biochemistry, North Carolina State University, 128 Polk Hall, Raleigh, NC 27695-7622, USA.


Protein-water interactions are key to biological function. They have an underlying dynamic component that pervades the functional roles associated both with particular systems and with the properties of proteins in general. This article focuses on the specific ways in which the dynamics of water are important to protein structure, motion and adaptability to changes in the protein environment.

[Indexed for MEDLINE]

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