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Trends Biochem Sci. 2002 Apr;27(4):168-70.

BSD: a novel domain in transcription factors and synapse-associated proteins.

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  • 1EMBL, 69012 Heidelberg, Meyerhofstr. 1, and Max-Delbrueck-Centrum, Berlin, Germany.


This article describes a novel domain, BSD, that is present in basal transcription factors, synapse-associated proteins and several hypothetical proteins. It occurs in a variety of species ranging from primal protozoan to human. The BSD domain is characterized by three predicted alpha helices, which probably form a three-helical bundle, as well as by conserved tryptophan and phenylalanine residues, located at the C terminus of the domain.

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