Format

Send to

Choose Destination
Neuroradiology. 2002 Mar;44(3):216-22.

Differentiation of radiation necrosis from tumor progression using proton magnetic resonance spectroscopy.

Author information

1
Research Program Radiological Diagnostics and Therapy, Deutsches Krebsforschungszentrum (DKFZ), Heidelberg, Germany. h.schlemmer@dkfz-heidelberg.de

Abstract

We report on a young woman who was treated by stereotactic radiotherapy for recurrence of an initially resected low-grade astrocytoma. MRI follow-up examination 7 months after radiotherapy showed a gadolinium-DTPA-enhancing mass lesion indicative of high-grade tumor progression. This assumption was also supported by positron emission tomography with [2-18F]fluoro-2-deoxy-D-glucose (FDG-PET). In contrast, proton MR spectroscopy (1H-MRS) indicated radiation necrosis, which was confirmed histopathologically in surgical specimens. Subsequent follow-up examinations up to 19 months after surgery showed no evidence of tumor recurrence.

PMID:
11942375
DOI:
10.1007/s002340100703
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Springer
Loading ...
Support Center