Format

Send to

Choose Destination
J Cancer Res Clin Oncol. 2002 Apr;128(4):177-81. Epub 2002 Feb 23.

Immunostimulatory activity of cationic-lipid-nucleic-acid complexes against cancer.

Author information

1
Johnson & Johnson Research, 1 Central Avenue, Australian Technology Park, Eveleigh 1430, Australia. cdass@medau.jnj.com

Abstract

Recent studies have highlighted the immunostimulatory nature of nucleic acids and the enhancement of such immunostimulation when nucleic acids are complexed to cationic liposomes to form cationic-lipid-nucleic-acid-complexes or lipoplexes. While such immunostimulation may have deleterious consequences for nucleic acid delivery, especially in the field of gene therapy, it may be harnessed for efficacious usage against the various forms of cancer.

PMID:
11935307
DOI:
10.1007/s00432-001-0318-x
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Springer
Loading ...
Support Center