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Microbes Infect. 2002 Apr;4(4):449-60.

Macrophage migration inhibitory factor (MIF): mechanisms of action and role in disease.

Author information

1
Laboratory of Biochemistry, Institute for Interfacial Engineering, University of Stuttgart, 70569 Stuttgart, Germany.

Abstract

Macrophage migration inhibitory factor (MIF) is a unique cytokine and critical mediator of host defenses with a role in septic shock and chronic inflammatory and autoimmune diseases. Its mechanism of action is incompletely understood. Here, we attempt to correlate current knowledge on the molecular pathways of MIF activity with its functions in immunity and disease.

PMID:
11932196
DOI:
10.1016/s1286-4579(02)01560-5
[Indexed for MEDLINE]

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