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Postgrad Med J. 2002 Apr;78(918):216-24.

Mechanisms of bacterial pathogenicity.

Author information

1
Program in Molecular Pathogenesis and Immunity, Department of Microbiology and Immunology, Tulane University Health Sciences Center, New Orleans, Louisiana 70112, USA.

Abstract

Pathogenic bacteria utilise a number of mechanisms to cause disease in human hosts. Bacterial pathogens express a wide range of molecules that bind host cell targets to facilitate a variety of different host responses. The molecular strategies used by bacteria to interact with the host can be unique to specific pathogens or conserved across several different species. A key to fighting bacterial disease is the identification and characterisation of all these different strategies. The availability of complete genome sequences for several bacterial pathogens coupled with bioinformatics will lead to significant advances toward this goal.

PMID:
11930024
PMCID:
PMC1742320
DOI:
10.1136/pmj.78.918.216
[Indexed for MEDLINE]
Free PMC Article

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