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Emerg Infect Dis. 2002 Mar;8(3):278-82.

A European study on the relationship between antimicrobial use and antimicrobial resistance.

Author information

1
National Institute of Public Health and the Environment, Department of Infectious Disease Epidemiology, Postbak 75, PO Box 1, Antonie van Leeuwenhoeklaan 9, 3720 BA Bilthoven, the Netherlands. stef.bronzwaer@rivm.nl

Abstract

In Europe, antimicrobial resistance has been monitored since 1998 by the European Antimicrobial Resistance Surveillance System (EARSS). We examined the relationship between penicillin nonsusceptibility of invasive isolates of Streptococcus pneumoniae and antibiotic sales. Information was collected on 1998-99 resistance data for invasive isolates of S. pneumoniae to penicillin, based on surveillance data from EARSS and on outpatient sales during 1997 for beta-lactam antibiotics and macrolides. Our results show that in Europe antimicrobial resistance of S. pneumoniae to penicillin is correlated with use of beta-lactam antibiotics and macrolides.

PMID:
11927025
PMCID:
PMC2732471
DOI:
10.3201/eid0803.010192
[Indexed for MEDLINE]
Free PMC Article
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