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Int Arch Allergy Immunol. 2002 Feb;127(2):133-6.

Surrogate markers of disease in mastocytosis.

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1
Laboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892-1881, USA. cakin@niaid.nih.gov

Abstract

Measurement of surrogate mast cell-related products in blood or urine is often performed to assess disease extent in evaluating patients with mastocytosis. Serum tryptase and 24-hour urine histamine metabolites are the most commonly used surrogate markers of mastocytosis. In addition, several novel markers including soluble CD117 and soluble CD25 have been identified in recent studies. The utility and the pitfalls of each of these measurements are discussed.

PMID:
11919423
DOI:
48184
[Indexed for MEDLINE]
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