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Gastrointest Endosc Clin N Am. 2002 Jan;12(1):65-75.

Rationale for colonoscopy screening and estimated effectiveness in clinical practice.

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Department of Medicine, Indiana University School of Medicine and Indiana University Hospital, Indianapolis 46202, USA.


Colonoscopy screening has the highest anticipated level of effectiveness of the available colorectal cancer screening techniques. Its long-term cost-effectiveness is also comparable with or superior to other modalities. Evidence for the expected reduction in colorectal cancer incidence and mortality varies with colonoscopy screening from 50% to 90%, for reasons that are not fully understood. Maintaining a high standard of performance is critical with regard to achieving the highest level of effectiveness possible.

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