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Neuroradiology. 2002 Apr;44(4):333-7. Epub 2002 Feb 26.

Neuroradiological findings in two cases of isolated amyloidoma of the central nervous system.

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Department of Radiology, University of L'Aquila, Via Vetoio (Loc. Coppito), 67100 L'Aquila, Italy.


Neuroradiological findings in two cases of isolated cerebral amyloidoma are reported. Case 1: A 15-year-old male admitted because of left jacksonian seizure. Case 2: A 31-year-old man admitted because of temporal seizures. In both patients, CT scans showed spontaneously hyperdense and enhancing nodules. On MRI, lesions displayed signals isointense with surrounding edema on T1-weighted sequences and mildly hypointense on T2-weighted sequences if compared with edema; peripheral contrast enhancement after gadolinium administration was present. Histopathological examination of both specimens revealed the presence of acellular eosinophilic hyalinized material consistent with amyloid, forming confluent nodular masses in the white and gray matter.

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