Send to

Choose Destination
See comment in PubMed Commons below
Curr Psychiatry Rep. 2002 Apr;4(2):146-52.

Familial links between attention deficit hyperactivity disorder, conduct disorder, and bipolar disorder.

Author information

  • 1Massachusetts General Hospital, 15 Parkman Street, ACC-725, Boston, MA 02114, USA.


Although family, twin, and adoption studies indicate that attention deficit hyperactivity disorder (ADHD) is a familial condition with a robust genetic component, molecular genetic studies of candidate genes have produced inconsistent findings. One of the challenges to elucidating the genetic architecture of ADHD is its potential genetic heterogeneity. Therefore, efforts are needed to identify etiologically homogeneous subgroups of subjects with ADHD for use in genetic studies. The current article reviews evidence suggesting that parsing ADHD subjects based on comorbidity with conduct and bipolar disorders may yield familial subtypes that are suitable for genetic analyses.

[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Loading ...
    Support Center