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Curr Biol. 2002 Mar 19;12(6):R209-11.

Developmental biology: vasculogenesis is a wreck without RECK.

Author information

1
Department of Anatomy, University of California, San Francisco, CA 94143-0452, USA. bwelm@itsa.ucsf.edu

Abstract

The unique membrane-associated inhibitor of matrix metalloproteinases, RECK, is required for vascular maturation during embryogenesis. The phenotype of a loss of function mutation of RECK shows the importance of pericellular proteolysis in development.

PMID:
11909548
DOI:
10.1016/s0960-9822(02)00752-2
[Indexed for MEDLINE]
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