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Nat Rev Immunol. 2002 Jan;2(1):60-5.

A role for antigen in the maintenance of immunological memory.

Author information

1
Institute of Cell, Animal and Population Biology, University of Edinburgh, Ashworth Laboratories, UK. d.gray@ed.ac.uk

Abstract

The immune system has a memory that it exhibits in the enhanced and augmented responses the second time it meets an antigen. The memory is the result of a number of changes to the system brought about during the primary response. The most important of these changes is the formation of an expanded pool of antigen-specific memory cells. One of the enduring questions in immunology is how these memory cells are maintained for such long periods.

PMID:
11905839
DOI:
10.1038/nri706
[Indexed for MEDLINE]

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