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Nat Rev Cancer. 2001 Nov;1(2):130-41.

Cancer gene therapy: fringe or cutting edge?

Author information

1
University of California San Francisco, Cancer Research Institute, 94115, USA. mccormick@cc.ucsf.edu

Abstract

Direct targeting of cancer cells with gene therapy has the potential to treat cancer on the basis of its molecular characteristics. But although laboratory results have been extremely encouraging, many practical obstacles need to be overcome before gene therapy can fulfil its goals in the clinic. These issues are not trivial, but seem less formidable than the challenge of killing cancers selectively and rationally--a challenge that has been successfully addressed.

PMID:
11905804
DOI:
10.1038/35101008
[Indexed for MEDLINE]

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