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South Med J. 2002 Mar;95(3):331-3.

Ketorolac for pain management after abdominal surgical procedures in infants.

Author information

1
Department of Surgery, Children's Hospital at University of Missouri Hospitals and Clinics, Columbia, USA.

Abstract

BACKGROUND:

While the use of intravenous ketorolac in infants less than 6 months old has not been previously reported, ketorolac may reduce opioid use and prevent opioid-associated side effects that are frequent in this age group. We reviewed our experience with ketorolac in infants to develop recommendations for using it after abdominal surgery.

METHODS:

We reviewed the records of 10 infants less than 6 months old who received ketorolac supplemented with morphine and 8 infants who received morphine alone for pain after abdominal surgery.

RESULTS:

Infants receiving ketorolac required less morphine than infants receiving morphine alone in the first 48 hours after surgery. Four patients receiving ketorolac did not require any supplemental morphine.

CONCLUSIONS:

Ketorolac reduces the amount of morphine required after abdominal surgery in infants less than 6 months old. The use of ketorolac deserves further study as a method of reducing opioid-associated adverse effects in this patient group.

PMID:
11902701
[Indexed for MEDLINE]

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