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J Photochem Photobiol B. 2002 Mar;66(2):148-52.

ATP synthesis in the disk membranes of rod outer segments of bovine retina.

Author information

1
Istituto di Biofisica, Facoltá di Medicina, Universitá di Genova, Corso Europa, I-16132 Genoa, Italy. pepe@ibf.unige.it

Abstract

ATP is synthesized on the disk membrane isolated from rod outer segments of the bovine retina. Together with a slow component which accounted for a constant rate of about 22 nmol ATP/min/mg of protein and which was due to the adenylate kinase activity, a fast component with a maximal activity of about 58 nmol ATP/min/mg of protein was measured at physiological calcium concentrations. This fast activity disappeared in the presence of the Ca(2+) ionophore A23187, was inhibited by vanadate or thapsigargin but not by oligomycin, suggesting that this ATP synthesis is due to the reversal functioning of the Ca(2+)-ATPase previously found on the disk membranes.

PMID:
11897515
[Indexed for MEDLINE]

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