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Neuron. 2002 Feb 28;33(5):668-71.

Toward an understanding of the brain substrates of reward in humans.

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  • 1Cognitive Neurology and Alzheimer's Disease Center, Northwestern University Medical School, 320 East Superior, Searle 11-465, Chicago, IL 60611, USA.


A network of brain regions has been implicated in food-reward processing. now provide evidence that this network is differentially modulated by anticipation versus receipt of a food reward and suggest an additional effect of valence of the stimulus.

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